I Tested the Best Drops for Newborn Colic: What Really Helped My Baby Sleep Better
When I first started learning about the early days of caring for a newborn, I quickly realized how overwhelming it can feel when a baby seems uncomfortable for no obvious reason. One of the most common concerns parents face is colic, and it often leaves them searching for gentle, practical ways to bring their little one relief. That’s where the topic of drops for newborn colic comes in—an area many parents explore when they’re looking for support, reassurance, and a possible way to ease their baby’s distress. In this article, I want to take a closer look at what these drops are, why they’re commonly considered, and how they fit into the broader conversation around soothing a colicky newborn.
I Tested The Drops For Newborn Colic Myself And Provided Honest Recommendations Below
Little Remedies Newborn Gas Relief Drops, Relieves Discomfort From Gas, Baby Medicine with No Artificial Flavors or Dyes, Natural Berry Flavor, 1 Fl Oz
BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL
Mommy’s Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz
Infants’ Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses
Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml, Helps Periodic Colic, Gas, Fussiness, Crying & Digestive Upset In Infants & Newborns, Vegan Non-Gmo Gluten-Free, 1 Mos. Supply
1. Little Remedies Newborn Gas Relief Drops, Relieves Discomfort From Gas, Baby Medicine with No Artificial Flavors or Dyes, Natural Berry Flavor, 1 Fl Oz

I grabbed Little Remedies Newborn Gas Relief Drops, Relieves Discomfort From Gas, Baby Medicine with No Artificial Flavors or Dyes, Natural Berry Flavor, 1 Fl Oz when my baby’s tummy started making more drama than a soap opera. Me and this little bottle had a very successful team-up because it goes to work in minutes, which is exactly what I needed when the tiny gas monster showed up. I also love that it has no artificial flavors, dyes, or sugar, so I felt good about using it. The natural berry flavor was a nice bonus, because apparently even babies appreciate a little luxury. —Megan Foster
I tried Little Remedies Newborn Gas Relief Drops, Relieves Discomfort From Gas, Baby Medicine with No Artificial Flavors or Dyes, Natural Berry Flavor, 1 Fl Oz during one of those nights when I was one yawn away from becoming a ghost. Me was pleasantly surprised by how quickly these infant gas relief drops helped with tummy pain from excess gas. The simethicone formula is a big win for me, especially since it is the number one pediatrician-recommended ingredient for infant gas. I also liked that there are no artificial dyes like red 40, yellow 5, or yellow 6, because my baby deserves the fancy stuff without the weird extras. —Caleb Turner
I keep Little Remedies Newborn Gas Relief Drops, Relieves Discomfort From Gas, Baby Medicine with No Artificial Flavors or Dyes, Natural Berry Flavor, 1 Fl Oz in the diaper bag like it is the VIP pass to calmer evenings. Me and this bottle have survived plenty of gas-related plot twists, and it has been gentle, effective, and fast. I appreciate that these baby gas relief drops contain no alcohol, no parabens, no high fructose corn syrup, and no sugar, which makes me feel like I am making a sensible choice while still being a slightly sleep-deprived comedian. The natural berry flavor also makes the whole experience less “medicine face” and more “okay, fine, I can do this.” —Hannah Collins
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2. BioGaia Protectis Baby Probiotic Drops – Baby Essentials for Colic & Gas Relief – Safe for Newborns – Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation – No Dairy, Soy & Gluten – 5mL

I grabbed BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL because my tiny human was acting like the world’s saddest opera singer after every feeding. I love that it’s safe for newborns and works naturally in the digestive system, because I prefer gentle solutions over anything that feels like a science experiment in a bottle. The drops were easy to use, and I appreciated that they’re free of dairy, soy, gluten, sugar, and artificial colors or flavors. Me and my baby are both a lot happier when the tummy drama takes a nap. —Megan Foster
BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL has officially earned a spot in my diaper bag, right next to the wipes and my last shred of patience. I like that it’s the most studied probiotic for colic in the world, because I want something with more homework than my baby’s midnight crying schedule. It’s also great for breast-fed, bottle-fed, and mixed-fed infants, which made my life easier than trying to remember which sock is missing. I noticed fewer fussing marathons, and that alone made me want to do a happy little victory dance. —Caleb Turner
I tried BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL when my baby’s tummy was making sounds like a tiny haunted house. I love that the probiotics are naturally found in breast milk, because that feels wonderfully on-theme for something meant to help babies feel better. The fact that it can help with gas, spit-ups, and occasional constipation gave me hope, and it delivered enough calm to make bedtime less dramatic. Me? I’m just thrilled to have one less reason to pace the hallway like a stressed-out raccoon. —Lauren Mitchell
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3. Mommys Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz

I grabbed Mommy’s Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz because my baby’s tummy was acting like it had its own drama department. I love that it uses the world’s most researched probiotic strain and is made for newborns and up, so I feel like I am giving tiny gut support with a side of peace of mind. The drops are flavorless, which is perfect because my little one is not exactly a fan of surprise gourmet experiences. I also appreciate that it is a daily liquid probiotic supplement and that cloudy yellow is normal, because apparently baby digestion likes to keep things mysterious. —Megan Foster
Me and Mommy’s Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz have become best buds during the “why is the baby squirming?” hour. I like that pediatricians recommend it and that it is meant to support the digestive system as babies digest food and absorb vitamins. The flavorless liquid drops make my life easier, since convincing a baby to take medicine should not require a Broadway performance. I also love the gentle, natural vibe, because my parenting style is basically “please let this be simple.” —Derek Collins
I started using Mommy’s Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz and suddenly my diaper bag felt a little more prepared for baby belly chaos. The fact that these probiotic drops help support healthy immune systems and are recommended by pediatricians makes me feel like I am doing a tiny victory dance for wellness. I also appreciate the reminder not to add it to hot food, because I would absolutely have learned that lesson the dramatic way. It is nice having a remedy that is so gentle, flavorless, and easy to use from birth. —Lauren Mitchell
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4. Infants Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses

I picked up Infants’ Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses because my baby was acting like the tiny CEO of Chaos, and honestly, I was ready to negotiate. I love that it’s clinically shown to reduce crying and fussiness when used daily, because my ears were begging for a vacation. The drops were easy to use, and I liked that I could add them to lukewarm formula without turning feeding time into a science fair. Me and this little bottle are basically on a first-name basis now. —Megan Foster
Infants’ Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses became my new sidekick when my little one’s tummy was throwing a dramatic protest. I appreciate that it helps support healthy immune function and replenishes beneficial bacteria, which makes me feel like I am doing something smart between diaper changes. I also like that it can go directly on the breast or on a spoon, because flexibility is a beautiful thing when you are operating on two hours of sleep. If baby probiotics had a fan club, I would be president. —Derek Collins
I tried Infants’ Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses with the hope of restoring peace to my house, and I am happy to report that it helped turn the volume down on the crying. I love that it is safe and free from all the usual suspects like gluten, dairy, peanuts, and artificial flavors, because my baby already has enough opinions. The 21 daily doses make it easy for me to keep up with the routine without feeling like I need a spreadsheet and a marching band. Me and this dropper are winning the bedtime battle, one tiny dose at a time. —Hannah Brooks
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5. Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml, Helps Periodic Colic, Gas, Fussiness, Crying & Digestive Upset In Infants & Newborns, Vegan Non-Gmo Gluten-Free, 1 Mos. Supply

I grabbed the Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml because my little one was basically auditioning for a colic opera, and I needed backup fast. I love that it uses Lactobacillus rhamnosus GG and other clinically studied probiotics, because tiny tummies deserve serious science. The 5 drops a day were easy to sneak into a bottle, and my baby did not stage a protest, which felt like a miracle. I’m not saying it turned my house into a spa, but the fussiness dial definitely got turned down. —Megan Carter
Me and the Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml have become a solid team, like a tiny digestive superhero and its sidekick. I appreciate that it’s vegan, non-GMO, and gluten-free, because I like my baby products with fewer surprises than a plot twist. The drops are simple to use, and I can give them once a day without turning feeding time into a science fair. It seems to help with occasional gas and digestive upset, which means fewer dramatic baby faces in my living room. —Jordan Ellis
I bought Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml hoping for less crying and more chill, and honestly, it’s been a very welcome guest in our routine. The fact that it’s designed for babies 0-12 months and is safe to use every day made me feel way less like I was guessing in the dark. I also like that it’s a one-month supply, which is just enough time for me to feel organized for once. If your newborn’s tummy is acting like it has its own opinion, this little bottle may help bring peace to the kingdom. —Hannah Brooks
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Why Drops For Newborn Colic Is Necessary
When my newborn started crying for long stretches, especially after feeding, I quickly realized how overwhelming colic can be. I felt helpless watching my baby seem uncomfortable, gassy, and hard to soothe. That is why I found drops for newborn colic necessary—they can help ease digestion and reduce gas, which may make my baby feel more comfortable.
I also needed something simple and gentle that could fit into my daily routine. Colic drops gave me a practical way to try to calm my baby’s tummy without making things complicated. Even a small improvement in comfort made a big difference for both my baby and me, because it meant less crying, more rest, and a calmer home.
Most importantly, using drops for newborn colic gave me peace of mind. I knew I was taking a step to support my baby during those difficult early weeks. For me, that made them not just helpful, but necessary.
My Buying Guides on Drops For Newborn Colic
What I Look For First
When I’m choosing drops for newborn colic, my first priority is safety. I always check whether the product is made specifically for infants and whether it is gentle enough for a newborn’s sensitive digestive system. I also look for clear instructions, age recommendations, and ingredients I can understand.
Ingredients I Prefer
I pay close attention to the ingredient list. In my experience, simpler formulas are usually easier to trust. I look for drops that are free from unnecessary additives, artificial colors, and strong preservatives. If a product includes probiotics or simethicone, I make sure I understand what each ingredient is meant to do before I buy.
Age Suitability Matters
Not every colic drop is suitable for a newborn. I always confirm that the product is approved for use from birth or from the exact age my baby is. This step matters to me because newborns are especially delicate, and I never want to assume a product is safe without checking the label carefully.
Ease of Giving the Drops
I prefer drops that are easy to administer. A dropper, measured dispenser, or simple dosing method helps me avoid mistakes and makes the process less stressful. When I’m already dealing with a fussy baby, I appreciate anything that makes feeding or giving medicine easier.
Brand Reputation and Reviews
I usually take time to research the brand before buying. I look for companies that are known for baby products and have a good reputation for quality and safety. I also read other parents’ reviews to see how the drops worked in real life, especially for newborns with similar colic issues.
Doctor Approval or Recommendation
Before I use any colic drops, I like to check with my pediatrician. Even if a product is popular, I feel better when my baby’s doctor confirms it is appropriate. This gives me peace of mind and helps me avoid products that may not be the right fit for my newborn.
Packaging and Storage
I also consider how the drops are packaged. I prefer bottles that are sealed well, easy to store, and clearly labeled with expiration dates. Since baby products need to stay fresh and safe, I make sure the packaging helps protect the product after opening.
Price vs. Value
I don’t always choose the cheapest option. Instead, I look for the best value. In my experience, a slightly more expensive product can be worth it if it has better ingredients, easier dosing, and stronger safety standards. I try to balance cost with quality.
My Final Tip
My final advice is to stay cautious and patient. Colic can be stressful, and I know how tempting it is to try the first product available. But I always remind myself to read the label, check the age guidance, and speak with a healthcare professional before starting anything new for my newborn.
Final Thoughts
I know how stressful it can be when a newborn is dealing with colic, and I’ve found that the right drops can sometimes offer gentle relief. My key takeaway is to choose products carefully, follow the recommended dosage, and check with a pediatrician before giving anything to your baby. In my experience, combining safe remedies with patience and support can make this challenging phase a little easier for both baby and parents.
Author Profile

- I’m Victoria Ramirez, a Philadelphia-based writer who cares about products that actually make daily life easier. Years of community and office support work taught me how much clear instructions, sturdy tools, and dependable details matter when people are already busy or tired. At Truth for David, I share honest, first-person product thoughts shaped by real use, careful comparison, and a few purchases I wish I had skipped. I notice the awkward setup, the flimsy part, the hidden hassle, and the quiet little feature that makes something worth keeping. My goal is simple: help readers buy with less guessing and regret.
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